AbobotulinumtoxinA widely used for upper‑face lines and larger zones where characteristic spread is beneficial. Indications typically include glabellar frown lines, crow’s feet and horizontal forehead lines under trained administration. Onset generally appears within several days with effects maintained temporarily before natural recovery of activity. Dosing and injection mapping are individualized to anatomy and muscle strength; units are not interchangeable across brands.
Individualized units per muscle and zone; intramuscular injections by licensed professionals using mapped patterns.
Common: injection‑site pain, bruising, headache. Rare: eyelid ptosis or asymmetry; seek urgent care for swallowing, speech or breathing problems.
Blocks acetylcholine release at neuromuscular junctions to relax targeted muscles temporarily.
Avoid alcohol 24h before and after treatment—vasodilation increases bleeding/bruising and may slow recovery.
Not recommended in pregnancy—controlled safety data are lacking and systemic toxin exposure cannot be ruled out.
Not advised during breastfeeding—excretion in milk is unstudied; potential infant risk is unknown.
